Maine Molecular Quality Controls Xpert PML-RARA Control Panel C215, Xpert PML-RARA Linearity Panel C221

Maine Molecular Quality Controls has introduced new reference material for Cepheid's Xpert PML-RARA assay, the Xpert PML-RARA Control Panel C215 and the Xpert PML-RARA Linearity Panel C221. The promyelocytic leukemia gene (PML) and retinoic acid receptor-α protein (RARA) gene results in PML-RARA, an oncogenic fusion gene, which is a driver for acute promyelocytic leukemia. 

The control panel is an external reference material used to monitor the performance of nucleic acid testing procedures for the quantitative detection of PML-RARA transcript isoforms, bcr1, bcr2, bcr3, and ABL1 endogenous control mRNA transcript when analyzed using the Xpert PML-RARA assay on Cepheid's GeneXpert instrument. The linearity panel is intended to monitor the reportable range of nucleic acid testing procedures for the quantitative detection of PML-RARA transcript isoform bcr1 and ABL1 endogenous control mRNA transcript when analyzed with the Cepheid assay.