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Lexogen RiboCop rRNA Depletion Kit for Yeast

Lexogen has released its RiboCop rRNA Depletion Kit for Yeast. Total RNA is composed of large amounts of undesired ribosomal RNA (rRNA), which accounts for up to 95 percent of all transcripts in an RNA sample, Lexogen said. The RiboCop rRNA Depletion Kit for Yeast enables efficient removal of this rRNA so that equencing reads are focused to RNA of interest, which allows more samples to be multiplexed and significantly reduces the sequencing cost per sample, the company said. RiboCop's rRNA depletion technology is based on hybridization of rRNA to specifically designed oligos and removal with magnetic beads. Lexogen has also developed an algorithm to design specific probe mixes for maximum rRNA removal while keeping unwanted off-target effects at a minimum and preserving unbiased expression profiles. RiboCop is compatible with CORALL RNA-Seq V2 and all standard RNA-Seq library preparation protocols, the company said.