Logo

ImmunoIVD SPOT-it TREC & SMN1 Screening Kit

Oct 08, 2021

ImmunoIVD, a Stockholm-based diagnostic company specializing in severe combined immunodeficiency (SCID) newborn screening, has launched the CE IVD marked SPOT-it TREC & SMN1 Screening kit in the EU. The real-time qPCR assay is designed to simultaneously screen or SCID and spinal muscular atrophy (SMA) in newborns using DNA extracted from fresh, dried blood spots sampled on filter paper. The assay is based on the same plate-stacking procedure as the SPOT-it SCID screening assays, making it efficient and affordable for small to medium sized screening laboratories, a company spokesperson said. SCID screening is performed by semi-quantification of T-cell receptor excision circle, while SMA screening is performed through the qualitative detection of exon 7 of the SMN1 gene, according to the company's website.

Breaking News
The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.