Logo

Illumina Dragen v4.0

Jul 27, 2022

Illumina has released Dragen v4.0, which it said has expanded capabilities for oncology, pharmacogenomics, single-cell sequencing, and population genomics. The new version enables calling of 20 Tier 1 pharmacogenomics genes and supports genotyping of complex genes, integrates the latest Expansion Hunter v5 for short tandem repeat expansions with an expanded catalog of loci, includes a new end-to-end imputation pipeline for low-pass whole-genome sequencing, and adds single-cell ATAC-seq (assay for transposase-accessible chromatin by sequencing) and single-cell multiomics pipelines.

Breaking News
The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.