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Dovetail Genomics Human and Mouse Pan Promoter Enrichment Kits

Dovetail Genomics announced its new line of capture Hi-C targeted enrichment panels. The Human Pan Promoter Enrichment Kit and Mouse Pan Promoter Enrichment Kits incorporate target enrichment technology from Twist Bioscience with Micro-C and Omni-C assays to enable interrogation of chromatin topology surrounding 80,000 coding and non-coding gene promoters.

The products increase sensitivity and resolution while reducing the sequencing burden by more than 90 percent. They utilize sequence-independent nucleases for superior coverage compared to restriction enzyme-based Hi-C methodologies. 

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.