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Devyser LynchFAP, BRCA PALB2

Devyser has launched two new hereditary cancer sequencing test kits, Devyser LynchFAP and Devyser BRCA PALB2.

Devyser LynchFAP analyzes PMS2 and nine other genes associated with hereditary colorectal cancer syndromes and is designed to localize genetic variants to PMS2 and its pseudogene PMS2CL.

Devyser BRCA PALB2 analyzes BRCA1, BRCA2, and PALB2, the three most important genes involved in breast cancer risk. It can be used to sequence DNA from blood as well as from tumor tissue.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.