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Cytek Biosciences 20-Color Acute Myeloid Leukemia Panel

Cytek Biosciences has launched a 20-color acute myeloid leukemia (AML) panel. The multiparametric single-tube flow cytometry assay is for research use only, and is intended to aid researchers in the development of AML therapies. The single-tube format eliminates the use of redundant reagents, and the assay can run on any Cytek Auora or Northern Lights system equipped with violet, blue, and red lasers, the company said. Potential applications include identifying and characterizing normal and aberrant cells, immunophenotyping, and evaluating measurable residual disease in AML samples, the company noted.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.