BioSkryb Genomics ResolveOme and BaseJumper

BioSkryb Genomics has launched the ResolveOme Whole-Genome and Transcriptome Amplification System and BaseJumper Bioinformatics Platform.

Single-cell methods generally can only decode a limited portion of the genome or transcriptome, or rely on bulk samples, which lowers resolution and can be time-intensive, BioSkryb noted. ResolveOme addresses these limitations through its single-cell whole-genome amplification technique that combines the company's primary template-directed amplification (PTA) method with full-transcript reverse transcription. As a result, ResolveOme enables the simultaneous exploration the whole genome and whole mRNA transcriptome from the same single cell, the company said. Additionally, the assay can be used to examine the whole exome or smaller targeted portions of the genome based on researcher needs.

BaseJumper has been designed to complement ResolveOme by streamlining the process of single-cell informatics at scale. The platform enables the rapid organization and mapping of multiomic (DNA, RNA, and protein) data generated by the ResolveOme system so researchers can easily interpret and visualize large data sets through dynamic filtering capabilities and a suite of visualization applications, BioSkryb said.