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Bio-Techne RNAscope HiPlex12 Flex Kit

Bio-Techne has launched its RNAscope HiPlex12 Flex Kit for use with the Standard BioTools Hyperion Imaging System. The kit enables visualization of highly multiplexed RNA biomarkers using the Hyperion XTi or earlier models of the Hyperion Imaging System and allows for the simultaneous detection and quantification of more than 40 biomarkers from any tissue sample in a single imaging step. The multiomic workflow provides a method to incorporate Maxpar Antibodies from Standard BioTools during sample preparation and will enable users to illuminate changes in cell phenotypes and function across a wide range of diseases using standard formalin-fixed paraffin-embedded tissue pathology slides, the company said.

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.