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Bio-Rad Molecular Blood Screening Controls for HBV, HCV, and HIV-1

Bio-Rad Laboratories said this week that its Exact Diagnostics HBV, HCV, and HIV-1 Screen Controls are now available to laboratories in Europe after having received CE IVD marking earlier this year. These controls are designed to monitor the performance of blood donor screening assays, including extraction, amplification, and detection, and are calibrated against WHO International Standards for HBV, HCV, and HIV-1. The products are made of whole viruses in a high-quality citrate plasma matrix to ensure lot-to-lot reproducibility, have an 18-month shelf life from date of manufacture (when stored at -20° C or below), and have a 24-hour stability (when stored at 2-8° C).

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.