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Bio-Rad ddPlex ESR1 Mutation Detection Kit

Bio-Rad Laboratories has launched its first ultrasensitive multiplexed digital PCR assay, the ddPlex ESR1 Mutation Detection Kit to aid translational research, therapy selection, and disease monitoring. Designed for use on the Bio-Rad QX600 Droplet Digital PCR System, this research-use assay enables simultaneous detection, discrimination, and absolute quantification of seven known relevant ESR1 mutations in a single well with analytical sensitivity down to 0.01 percent variant allele fraction. The kit includes controls and enables same-day results from either circulating tumor DNA from plasma or DNA from formalin-fixed paraffin-embedded (FFPE) tissue samples. The assay is the first to license NuProbe's allele enrichment technology under a previously announced collaboration.