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BillionToOne Unity sgNIPT

Molecular diagnostics company BillionToOne has launched its fetal antigen single-gene non-invasive prenatal test (sgNIPT) as part of the firm's Unity Screen. The test is used in pregnant patients who are alloimmunized with C, c, D, E, Duffy, or Kell red blood cell antibodies to identify genetic variants that code for corresponding fetal antigens. The test is used at 10 or more weeks of gestation in patients who doctors suspect are at elevated risk of hemolytic disease of the fetus and newborn (HDFN).

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.