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AWS Amazon Genomics CLI

Amazon Web Services has released Amazon Genomics CLI, an open-source software tool for managing and processing large-scale genomics data on the AWS cloud. The tool is meant to improve integration of a wide range of popular bioinformatics software with AWS services, including the Amazon Elastic Container Service, Amazon Dynamo DB, and the Amazon Simple Storage Service. While Genomics CLI itself is free, users must pay for any AWS resources the software creates.   

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.