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Artisan Bio Star-CRISPR

Artisan Bio this week launched what it calls a "CRISPR-based one-stop shop" based on its Star-CRISPR platform for the research and commercialization of cell and gene therapies. Star-CRISPR includes a proprietary nuclease and guiding architecture, and its performance has been validated in T, NK, and iPS cells, with high gene knock-in and knock-out efficiencies, multiplexed editing capabilities, and large payload deliveries, the company said.

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.