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Arima Genomics Arima-Hic+ FFPE Kit and Arima-Sv Bioinformatics Pipeline

Arima Genomics has launched the Arima-Hic+ FFPE kit, which expands the Arima-Hic+ workflow to formalin-fixed paraffin-embedded (FFPE) tissues, and the new Arima-Sv pipeline, allowing researchers to identify structural variants from their 3D genomic data from a broad range of sample types. According to the company, the kit combined with the bioinformatic pipeline will provide researchers a robust workflow to identify structural variants using FFPE tissue samples and short-read sequencing, elucidating connections among the 3D genome, gene function, and disease processes. These tools can also be used for a wide range of translational research areas including cancer, blood and neurological disorders, and immune diseases, where FFPE tissues are a critical archival and clinical sample type.


The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.