Logo

Angle Portrait Flex CTC Assay

Sep 07, 2023

Angle said this week that it has launched the Portrait Flex CTC assay as a service provided by its Onc-ADaPT GCP-compliant laboratories. The Flex test uses immunofluorescence staining for epithelial, mesenchymal, blood lineage, and nuclear markers on cells isolated with its Parsortix system, with the opportunity to include additional biomarkers tailored to customer needs. Angle claims an analytical sensitivity of more than 93 percent and an analytical specificity of over 95 percent for both epithelial and mesenchymal markers.

Breaking News
The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.