Alithea Genomics Mercurius Full-Length DRUG-Seq Library Prep Technology

Alithea Genomics has launched the Mercurius full-length DRUG-Seq library prep technology, which combines massive sample multiplexing and full transcript coverage in an extraction-free RNA-seq workflow. The technology allows the preparation of Illumina-compatible RNA sequencing libraries for up to 384 samples. The kit enables full-length transcript coverage, as opposed to 3' coverage of the standard DRUG-seq kit, detecting over 40,000 different transcripts at only 4 million reads/sample, reaching similar levels to non-multiplexed gold-standard techniques, the company said. Furthermore, the technology allows the detection of different isoforms, splicing variants, and alternative promoters, Alithea said.