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10x Genomics: Barcode-Enabled Antigen Mapping (BEAM)

10x Genomics has launched Barcode-Enabled Antigen Mapping (BEAM,) a kit for antibody and T-cell receptor discovery on the company's Chromium single-cell immune profiling platform. The kit provides hundreds of antigen-receptor pairs with single-cell gene expression data, and is designed to enable screening of multiple antigens against thousands of B or T cells to identify novel and rare antigen-specific repertoires. 10x is accepting preorders for BEAM and expects to begin shipping in December.

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.