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New Products Posted to GenomeWeb This Week: OmniTier, Synthego, Trovagene, More

OmniTier CompStor Assembly

OmniTier has introduced CompStor Assembly for de novo DNA assembly and reference alignment. Designed for short-read next-generation sequencing data, CompStor Assembly reduces assembly times and improves assembly quality on low-cost hardware compared to currently available assemblers, the company said. Using CompStor Assembly and eight CompStor Assembly server nodes, de novo assembly of a human genome can be achieved in about eight minutes. This performance equals the assembly time previously achieved with the NERSC's Cray XC30 advanced supercomputer, using 15,360 processor cores and DRAM-based algorithm implementations, OmniTier noted. By contrast, CompStor Assembly nodes are standard servers based on low-cost x86 Intel processors and tiered DRAM and NVMe SSDs.


Synthego CRISPRevolution Gene Knockout Kit

Synthego has launched its new CRISPRevolution Gene Knockout Kit (GKO) for all CRISPR researchers, including those developing emerging therapeutic modalities with increasing genome engineering demands such as CAR-T immunotherapy and treatment of monogenic diseases. The CRISPRevolution GKO includes four top-scoring guides from Synthego's CRISPR Design Tool, provided as high efficiency chemically modified synthetic sgRNAs, SpCas9 protein, and control reagents to optimize transfection protocols. This kit has an easy-to-use experimental workflow, and comes with a money-back guarantee on 50 percent or better editing in any human cell type for research use.


Trovagene NextCollect Kit

Trovagene has announced that its NextCollect urine collection and DNA preservation kit is now available, for research use only, to clinical research laboratories and pharmaceutical customers. The kit is a high-volume urine specimen collection and stabilization tool, and is available for both existing contracted clients and to new customers through an online web portal, the company said. Additionally, Trovagene said that it plans to make DNA Isolation Buffer Kits that complement NextCollect available in early 2018, using methods developed as part of the firm's Trovera ctDNA tests.


For more new products and services, please visit the New Products page on our website.

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.