Agilent SureGuide CRISPR Libraries for Functional Genomics
Agilent Technologies has launched new CRISPR/Cas9 guide RNA (gRNA) libraries for pooled screening. Agilent is offering both genome-scale CRISPR knockout (GeCKO) and customized SureGuide gRNA libraries for functional genomics in three varieties: ready-to-package GeCKO plasmid libraries, ready-to-clone custom libraries that can be prepared for delivery with SureVector cloning kits, and ready-to-amplify custom libraries for total control over library design.
10X Genomics Chromium Single Cell Controller
10X Genomics has launched the Chromium Single Cell Controller, a massively scalable tool for comprehensive single cell analysis. The instrument can interrogate hundreds to millions of cells, and features a simple and comprehensive workflow which enables users to quickly and easily prepare single cell sequencing libraries in less than one workday, the company said. Additionally, the instrument includes an easy-to-use software suite for rapid analysis and visualization of very large single cell datasets. It can also support a variety of applications, including the existing Chromium Single Cell 3' Solution for single cell transcriptomics. The system is accompanied by Chromium Single Cell 3' reagent kits and features full compatibility with Illumina HiSeq, NextSeq and MiSeq sequencers. It's currently available at an introductory price of $50,000.
Thermo Fisher Scientific PharmacoScan
Thermo Fisher Scientific has introduced the PharmacoScan, a microarray-based research tool that contains relevant pharmacogenomic markers of the absorption, distribution, metabolism, and excretion (ADME) pathways of commonly prescribed medicines. Using PharmacoScan, researchers can interrogate more than 4,600 markers in nearly 1,200 genes involved in pharmacogenomics pathways with a single assay. The solution is enabled by the Axiom genotyping solution and automated GeneTitan multi-channel array plate processing instrument, and enables lot-to-lot reproducibility and data consistency and high-throughput and affordable sample processing. The product was developed in collaboration with the Clinical Pharmacogenetics Implementation Consortium, PharmaADME, and PharmGKB. Early-access customers include the University of Montreal Hospital Research Centre, the University of Alberta, and leading genomic service laboratories, Thermo Fisher said.
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