Thermo Fisher Scientific MagMax Nucleic Acid Isolation Kits
Thermo Fisher Scientific has launched several new MagMax nucleic acid isolation kits. According to the firm, the kits use MagMax magnetic bead technology and are optimized for Thermo's KingFisher Flex and Duo Prime instruments. The firm designed the MagMax Microbiome Ultra Nucleic Acid Isolation Kit to isolate RNA and DNA from microbiome samples such as stool and soil samples. Researchers can use Thermo's MagMax Viral/Pathogen Ultra Nucleic Acid Isolation Kit to recover RNA and DNA from difficult-to-lyse microorganisms, including gram-positive bacteria, yeast, and fungi. The firm said that its MagMax Viral/Pathogen Nucleic Acid Isolation Kit can isolate RNA and DNA from viral particles and gram-negative bacteria found in samples such as blood, swabs, urine, and viral transport media.
New England Biolabs NEBNext Enzymatic Methyl-seq
New England Biolabs has launched NEBNext Enzymatic Methyl-seq (EM-seq), an enzyme-based method for methylation sequencing that is an alternative to bisulfite sequencing. According to the firm, the EM-seq kit involves a two-step enzymatic conversion that first protects 5-methylcytosine and 5-hydroxymethylcytosine from deamination using TET2 and an oxidation enhancer. The conversion then deaminates unmethylated cytosines, converting them to uracil. Because the process does not rely on chemical treatment, as with bisulfite conversion, the DNA is not damaged, according to the company. The kit includes the required reagents for EM-seq conversion and library preparation for sequencing on Illumina instruments.
Arc Bio Galileo Pathogen Solution, GPS-Transplant
Arc Bio has launched the Galileo Pathogen Solution product line and first product, GPS-Transplant, a research-use-only next-generation sequencing test to help monitor post-transplant patients for viral infections. GPS-Transplant detects the most common viral infections among transplant patients, including cytomegalovirus, Epstein–Barr virus, BK virus, and human adenovirus. The test also detects different variances and genotypes of the viruses, as well as more rare infections.
GPS-Transplant also offers researchers the ability to detect antiviral resistance mutations and performs simultaneous quantitative detection of more than 350 viral strains. The firm said that the kit is a sample-to-report solution built around the Illumina NGS platform that consists of reagents, built-in assay controls, as well as Galileo Analytics, a cloud-based software that provides rapid and reliable results, an intuitive user interface, and detailed reports. The analytics software leverages Arc Bio's curated pathogen database called ArcIve, and also incorporates AMR resistance prediction technology, which Arc Bio launched last year.
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