Oxford Nanopore Field Sequencing Kit
Oxford Nanopore Technologies has launched a Field Sequencing Kit for sequencing library preparation from genomic DNA that doesn't require refrigeration. The kit requires 400 nanograms of high molecular weight DNA as input, and generates libraries in 10 minutes using a two-step protocol. A transposase simultaneously cleaves template molecules and attaches tags to their ends. After that, rapid sequencing adapters are added to the tagged ends. The unopened kit is shipped cold and is stable for up to one month at 30° C and up to three months at 2° C to 8° C.
NRGene, Macrogen ArrayMagic
NRGene and Macrogen have launched a joint sequencing-based genotyping service called ArrayMagic, which the firms said provides ultra-high-density SNP genotying at a low cost per datapoint. As part of the service, the team will launch a dedicated website to advise customers on how to send samples to Macrogen. The partners will then employ a sequencing library prep method — developed by iGenomX — to create an ultra-low coverage sequencing dataset for each sample. NRGene will then apply its database and analytical tools to impute a high-resolution SNP set from the data.
HTG Molecular EdgeSeq Reveal
HTG Molecular said that it has launched its HTG EdgeSeq Reveal software. According to the firm, the software streamlines biomarker data analysis from samples analyzed with the HTG EdgeSeq Precision Immuno-Oncology Panel on its EdgeSeq system. When used with the panel, the software allows applications including immunophenotyping of tumor infiltration lymphocytes, monitoring of immunotherapy response biomarkers, and elucidating of immune-escape mechanisms know to drive disease progression. The firm said that users will be able to conduct molecular profiling using a wide variety of sample types, potentially allowing them to support translational applications and determine potential biomarkers for companion diagnostic development.
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