Skip to main content
Premium Trial:

Request an Annual Quote

New Products Posted to GenomeWeb: Fluidigm, Loop Genomics, Sema4

Fluidigm Advanta Solid Tumor NGS Library Prep Assay

Fluidigm has launched the Advanta Solid Tumor NGS Library Prep Assay for the simultaneous detection of somatic variants across 53 solid tumor genes using a microfluidic library prep workflow. The firm developed the assay for use with the Juno system, which automates the target enrichment of single-nucleotide variations, indels, and copy number variations for subsequent analysis on Illumina sequencing platforms. The assay comes with a new Juno LP 8.8.6 microfluidic cartridge that allows users to easily process up to six different panels simultaneously with 10-fold lower sample input. Users can also add new cancer markers to the Advanta panel using Fluidigm D3 assay design services, the company said.


Loop Genomics Microbiome Sequencing Sample Prep Kits

Loop Genomics has launched four new sample preparation kits for use on Illumina sequencers to help identify the presence and relative abundance of organisms in the human microbiome.

The kits include: a low biomass phased V1-V9 full-length 16S kit with picogram input amounts and zero human DNA background; a phased 18S-ITS1-ITS2 long-read solution for fungal mycobiome profiling that interrogates an approximately 2.5-kb contiguous region of the genome; a low biomass version of the fungal profiling kit; and a 16S read-cloud kit that offers V1-V9 coverage without V1-V9 phasing.


Sema4 Centrellis Health Intelligence Platform

Sema4 has launched several genomic testing services and digital tools as part of its Centrellis Health Intelligence Platform. According to the firm, the tools provide a comprehensive approach to track a patient's cancer, and are based on 250x tumor coverage and 100x normal coverage across all genes.

The research use only tools include: Patient Journey, which provides an interactive timeline visualization of the patient's health journey and offers services such as diagnoses, treatments, and molecular profiles; Cohort Builder, which offers the ability to define groups of patients according to specific parameters such has stage, histology, and treatments to understand treatment patterns, identify appropriate clinical trials, and allow data-driven decisions about patient care; and VONC, which is an automated variant curation platform using a wide array of databases to support curation of genetic information at scale with clinical evidence to recommend therapy decisions.

Using 100 million reads, the services provide clinical data about a wide range of genomic variants, gene fusion and alternative splicing, tumor mutational burden, and microsatellite instability, the firm said. Researchers can perform the services using fresh frozen, paraffin-embedded, bone marrow, blood, or saliva samples.


For more new products and services, please visit the New Products page on our website.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.