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New Products: Mar 6, 2009

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Sigma-Aldrich this week announced the launch of the Mission LentiPlex pooled human and murine shRNA libraries.

The Mission LentiPlex pooled shRNA libraries were developed from the entire RNAi Consortium-1 human and mouse collections of more than 158,000 shRNA constructs targeting approximately 16,000 human genes and approximately 16,000 mouse genes. Combining Sigma-Aldrich's high-throughput lentiviral production methodologies with the pooled library format enables researchers to perform genome-wide RNAi screens on various cell types.


NanoTherics this week announced the launch of its magnefect-nano system for gene transfection. The system uses a technique applying proprietary magnet configurations and oscillating array systems to promote particle/DNA uptake into cells.


Thermo Fisher Scientific announced this week that it will launch the Thermo Scientific Cellomics Comet v3.0 BioApplication at the Society of Toxicology annual meeting, to be held in Baltimore, Md., March 15-19. This new application uses a cell-based imaging approach for addressing the bottleneck of rapid and accurate DNA damage assessment based on the Comet assay.

The Comet BioApplication runs on the Thermo Scientific Cellomics ArrayScan VTI system, and provides automatic acquisition and quantification of Comet assays.

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The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.