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New Product Watch: Mar 1, 2011


Affymetrix this week launched its GeneChip miRNA 2.0 Array. The firm claims the new chip "offers the broadest coverage" of known microRNAs, encompassing 131 organisms, and doubles the content of its first- generation array by updating the mature miRNA, small cajal body-specific RNA, and small nucleolar RNA present on the chip.

The assay for Affy's miRNA array offering includes the use of Genisphere's FlashTag Biotin RNA Labeling Kit, and requires 45 minutes to carry out. The array, assay, and software are compatible with current GeneChip Systems, the company said.

MiRNAs discovered using the GeneChip miRNA 2.0 Array can be validated using Affy's new QuantiGene 2.0 miRNA Assay Kit. The kit uses reporter amplification and generates quantitative information directly from samples without the need for miRNA isolation, cDNA synthesis, or PCR, Affy claims. Detection probes are pre-validated for specificity and sensitivity and are designed to the same target sequences used in the GeneChip miRNA 2.0 Array.

Illumina this week launched the Infinium HD FFPE Restore Kit. The new product enables researchers to repair damaged DNA and perform whole-genome genotyping on highly degraded formalin-fixed and paraffin-embedded samples.

After using the kit, genotyping can be performed on two enabled Illumina arrays: the Human CytoSNP-FFPE and HumanOmniExpress-FFPE, Illumina said.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.