Cellecta Driver-Map Human Genome-Wide Expression Profiling Service
Cellecta has launched the Driver-Map human genome-wide expression profiling service, a targeted RNA expression method that enables quantitative expression analysis of all known 19,000 protein-coding genes in the human genome from as little as 10 pg of total RNA.
The method uses multiplexed RT-PCR directly from total RNA followed by next-generation sequencing, and employs a robust single-tube protocol with features that are particularly suitable to complex applications such as large-scale biomarker discovery and tumor microenvironment characterization. Cellecta noted that the method uses an optimized primer set that yields 1,000- to 10,000-fold dynamic range.
Leica Biosystems/Advanced Cell Diagnostics Aperio RNA ISH Algorithm
Leica Biosystems and Advanced Cell Diagnostics (a Bio-Techne brand) have announced the availability of the Aperio RNA ISH algorithm for use with ACD's RNAscope ISH assays.
This new offering builds on an existing collaboration between the companies to automate ACD's RNAscope assays on the Leica Biosystems BOND RX research staining platform. The new RNA ISH algorithm completes the automated RNA ISH workflow for researchers performing the RNAscope assay on the BOND RX, the companies said.
WaveSense has launched the nRichDx system for bulk isolation of target cells and nucleic acids from liquid biopsies. The new system uses WaveSense's proprietary paramagnetic bead technology to capture circulating tumor cells and cell-free DNA or RNA in quantities sufficient for subsequent next-generation sequencing or PCR analysis. The system can capture cells and nucleic acids from an array of sample types including blood, urine, and bone marrow, and is specifically designed and optimized for high-volume, low-yield specimens, the company said.
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