Neurological & Psychological Disorders News on research and diagnostic developments in neuroscience. Startup Circular Genomics Raises $4.5M in Seed Funding The company was founded earlier this year to commercialize a test for depression based on circular RNA biomarker technology. Linus Biotechnology Looks to Human 'Exposome' as Biomarker for Autism Spectrum Disorders Test Premium The Mount Sinai School of Medicine spinout plans to help diagnose autism spectrum disorders earlier by evaluating individuals' past environmental exposures. More Than Dozen Genetic Loci Linked to Amyotrophic Lateral Sclerosis Risk The risk loci highlight shared ties and differences between ALS and other neurodegenerative conditions, and further suggested a role for autophagy in ALS development. Analysis Estimates Psychiatric Disorder Risk from Specific Copy Number Variants in Danish Cohort The population-based analysis found that deletions and duplications in six genomic loci generally increased risk for autism spectrum disorder and ADHD. Multiomic Analysis of ALS Pinpoints Altered Lipid Metabolism as Potential Therapeutic Target Researchers analyzed spinal motor neurons and ocular motor neurons to identify shared metabolic perturbations in inherited and sporadic ALS. Jun 14, 2021 Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Jun 10, 2021 Alzheimer's Disease Meta-Analysis Identifies Novel Differentially Methylated Loci May 27, 2021 Large-Scale Depression Genetic Study Uncovers Additional Risk Loci, Ties to Potential Drugs May 26, 2021 23andMe Begins Reporting PGx Variants With Drug Info Under Recent FDA Clearance Premium May 21, 2021 NIH, Genomics England Launch Large-Scale Human Genome Sequencing Studies Using Nanopore Technology May 21, 2021 European Project to Harness Biobanks, EHRs to Develop Precision Psychiatry Tools Premium May 20, 2021 Rabid-Seq Method Offers NGS-Based View of Cellular Interactions in the Brain Premium May 19, 2021 Analysis Uncovers Hundreds of Autism-Linked Genes Using Evolution-Informed Approach May 17, 2021 Bipolar Disorder GWAS Meta-Analysis Points to Potential Treatment Targets May 6, 2021 Parkinson's Disease Progression Linked to Five Variants in Genome-Wide Survival Study May 5, 2021 Myriad Genetics Projects Return to Profitability by Year End, Details Long-Term Growth Plan Premium May 3, 2021 InformedDNA Partners With Gene Therapy Firm Passage Bio on Dementia Genetic Testing Apr 30, 2021 GWAS-Methylation Integration Could Help Identify Drug Repurposing Candidates for MS Premium Apr 29, 2021 Valted Seq Lands Exclusive Rights to Evaluate Johns Hopkins Neurodegenerative Disease Dx Assays Apr 28, 2021 Illumina, GeneDx Partner With University of Washington on Whole-Genome Sequencing Study in Kids Apr 13, 2021 Proteome-Wide Association Study of Depression Homes in on Potential Treatment Targets Apr 12, 2021 Sanford Health Looks to Improve Rare Disease Dx, Research With Congenica Technology Premium Apr 2, 2021 Alzheimer's Disease Genomes Lead to Novel Loci Involved in Synaptic Function Apr 2, 2021 Swiss Firm Marker Diagnostics Developing Saliva-Based Concussion Assay Premium Apr 1, 2021 Blood Methylation Analysis, Artificial Intelligence May Detect Alzheimer's Disease Early Load More Breaking News Pediatric Cardiomyopathy Exome Sequencing Study Suggests More Disease Genes to be Found People in the News: New Appointments at Helix, Pacific Biosciences, SomaLogic, More New Products Posted to GenomeWeb: Amoy Diagnostics, Akoya Biosciences, Congenica, Lucence In Brief This Week: BGI, Gencove, Cepheid, Biocartis, Biognosys, Co-Diagnostics, More Florida Lab Owner Pleads Guilty to $6.9M COVID-19 False Billing Scheme Pacific Biosciences Outlines Progress on Short-Read Sequencing at JPM, Partners With Canexia Health The Scan Close Panel Vote on Califf Nomination The New York Times reports there was a close committee vote to advance the nomination of Robert Califf to lead the US Food and Drug Administration to the full Senate. Task Force Reports on Scientific Integrity Nature News writes that that a new task force report recommends that the US establish a cross-agency scientific integrity council. Across the Hall Genetic testing, closed-circuit cameras, and more show how a traveler, without any contact, infected others at a New Zealand quarantine facility, CNN reports. Science Paper Examines Influence of Chromatin Modifications on Obsessive-Compulsive Disorder In Science this week: genes regulating chromatin modification may contribute to OCD risk.