Neurological & Psychological Disorders News on research and diagnostic developments in neuroscience. Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis The findings highlight the need for polygenic risk scores to not only be predictive but also provide additional information that cannot be captured elsewhere more easily. Committees Seek Information The New York Times reports two congressional committees are seeking information about the US Food and Drug Administration's approval of Biogen's Alzheimer's disease treatment. FinnGen Project's Role in Epilepsy, Drug Adherence Studies Showcased at ESHG Both studies relied on data collected via the FinnGen project, an international effort to collect genotype and health registry data on 500,000 people in Finland by 2023. Manipulation Concerns Raised Retraction Watch reports that a law firm has brought up concerns with the US Food and Drug Administration of possible data manipulation among a filing for an Alzheimer's disease treatment. PLOS Papers on SNP Mapping, Major Depressive Disorder in Pakistan, Salmonella Strains In PLOS this week: new approach to map SNPs, analysis of candidate genes for major depression disorder, and more. Apr 28, 2021 Illumina, GeneDx Partner With University of Washington on Whole-Genome Sequencing Study in Kids Apr 13, 2021 Proteome-Wide Association Study of Depression Homes in on Potential Treatment Targets Apr 12, 2021 Sanford Health Looks to Improve Rare Disease Dx, Research With Congenica Technology Premium Apr 2, 2021 Alzheimer's Disease Genomes Lead to Novel Loci Involved in Synaptic Function Apr 2, 2021 Swiss Firm Marker Diagnostics Developing Saliva-Based Concussion Assay Premium Apr 1, 2021 Blood Methylation Analysis, Artificial Intelligence May Detect Alzheimer's Disease Early Mar 22, 2021 Ultra-Rare Genetic Variants in Protocadherin Gene Linked to Schizophrenia Mar 15, 2021 Variantyx Raises $20M in Series C Financing Mar 8, 2021 Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders Mar 8, 2021 Norwegian Startup Pre Diagnostics Developing Monocyte Test for Presymptomatic Alzheimer's Disease Premium Mar 4, 2021 Datavant, Cerebral Palsy Research Network Seek Genetic Clues to CP Mar 2, 2021 NIH, Partners Commit $74.9M to New Phase of Alzheimer's Program Feb 25, 2021 New Alzheimer's Disease Genes Linked Through Transcriptome-Wide Study Feb 24, 2021 Cytox Gets CE Mark for Alzheimer's Disease Genetic Risk Test Feb 16, 2021 Two Studies Uncover Risk Loci for Age-Associated Neurodegenerative Disorders Feb 10, 2021 Tataa Biocenter Takes Majority Stake in Swedish Genetic Testing Firm Life Genomics Feb 8, 2021 Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region Feb 2, 2021 Exome Sequencing Provides Molecular Diagnosis in Portion of Cerebral Palsy Cases Jan 28, 2021 Million Veteran Program GWAS Uncovers Genetic Loci Linked to PTSD Jan 28, 2021 Alzheimer's Disease-Related Proteins Picked up in Proteome-Wide Association Study Load More Breaking News Vibrent Health, University of Maryland Medicine Partner for Population Health Initiative Polygenic Risk Scores for Breast, Prostate Cancer Adaptable for Cross-Ancestry Use, Study Shows Molecular Clonal Tracking Method Captures Lung Cancer Treatment Response, Resistance Features Oxford Nanopore Technologies to Raise £300M in IPO, Including £150M Investment by Oracle Thermo Fisher Scientific Receives CE Mark for TaqPath COVID-19 RNase P 2.0 Testing Kit Castle Biosciences Receives New York State Approval for DecisionDx DiffDx-Melanoma Test The Scan Tennessee's COVID-19 Sequencing The Tennessean reports that a state lab there can now run its own genome sequencing analyses of SARS-CoV-2 samples. Sanction Violation Charges A former professor has been charged with exporting genetic sequencing equipment to Iran in violation of US sanctions, the Miami Herald reports. Prenetics to Go Public Through SPAC Prenetics, a Hong Kong-based genomic and diagnostic company, is going public through a SPAC merger, according to 360Dx. Nature Papers Examine Genomes of Centenarians, Transcription-Coupled DNA Repair In Nature this week: analysis of centenarian genomes uncovers longevity-linked variants, and more.