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NEW YORK (GenomeWeb) – A major European Huntington's disease haplotype has ancient roots, according to a sequence-level investigation.

Huntington's disease is a dominantly inherited neurodegenerative disorder marked by an extended CAG trinucleotide repeat expansion in the coding sequence of the huntingtin gene HTT, and recent work has found that there are seven common haplotypes associated with Huntington's disease in Europeans.

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