NEW YORK (GenomeWeb) – A major European Huntington's disease haplotype has ancient roots, according to a sequence-level investigation.

Huntington's disease is a dominantly inherited neurodegenerative disorder marked by an extended CAG trinucleotide repeat expansion in the coding sequence of the huntingtin gene HTT, and recent work has found that there are seven common haplotypes associated with Huntington's disease in Europeans.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.