Childhood Mood, Behavioral Problems May Share Genetic Features With Some Adult Conditions

NEW YORK – Polygenic scores (PGS) developed using genetic risk variants identified in prior genome-wide association studies on adult mood conditions such as depression and neuroticism appear to be over-represented in children with social problems and other psychopathological traits, according to new research from an international team led by members of the Psychiatric Genomics Consortium's bipolar disorder and major depressive disorder working groups.