Neurological & Psychological Disorders
News on research and diagnostic developments in neuroscience.
Schmidt Futures Gives $50M for Life Science Research Including Single-Cell Proteomics Institute
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The philanthropy has joined hedge fund founder Ken Griffin to fund a new research facility headed by single-cell proteomics pioneer Nikolai Slavov.
Genetic Risk of Substance Use Disorders Untangled in Large-Scale GWAS Meta-Analysis
The study, of over 1 million individuals with European ancestry and almost 100,000 of African descent, found loci associated with general and substance-specific addiction.
Protein-Truncating Variants Confer Schizophrenia Risk Across Human Populations
A recent study also found two new genes involved in schizophrenia risk that could become potential therapeutic targets.
Exome Sequencing for Cerebral Palsy Has Sufficient Diagnostic Yield for First-Tier Test
A meta-analysis of prior studies found that the diagnostic yield of exome sequencing for cerebral palsy exceeded 31 percent, similar to other neurodevelopmental disorders.
APOE Missense Variant Linked to Increased Alzheimer's Disease Risk in African Americans
A case-control study found that the APOE ε3[R145C] variant, seen in 4 percent of African Americans, increases AD risk in individuals with the ε3/ε4 genotype.