Neurological & Psychological Disorders
News on research and diagnostic developments in neuroscience.
Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis
The findings highlight the need for polygenic risk scores to not only be predictive but also provide additional information that cannot be captured elsewhere more easily.
FinnGen Project's Role in Epilepsy, Drug Adherence Studies Showcased at ESHG
Both studies relied on data collected via the FinnGen project, an international effort to collect genotype and health registry data on 500,000 people in Finland by 2023.
Children With Autism May Have Underdeveloped Gut Microbiomes, Metagenomic Analysis Finds
The researchers are now developing a PCR-based diagnostic tool to evaluate the markers they found in a larger, independent cohort and across different populations.
Gene-Disrupting Ultra-Rare Variants More Common in Children With Autism Spectrum Disorder
The study's findings further support a multi-hit model for autism risk, especially among cases where autism runs in the family.
Multi-Ethnic Migraine GWAS Uncovers Risk Loci Specific to Sex, Ancestry
Investigators analyzed genetic data for more than half a million individuals, detecting susceptibility sites specific to women or European individuals.