The UPenn team will collect genetic information from outside patient cohorts, reorganize it in a streamlined process, and provide a database for downstream studies.
Researchers used CRISPR to engineer mice that have multiple genetic variants associated with late-onset AD to facilitate research into biomarkers and treatments.
Researchers used brain expression data from mice with well-documented sleep traits to identify gene networks that overlap with those in human depression.
In an epigenome-wide association study of depression, the researchers tied DNA methylation to disease symptoms and suggested a role for axon guidance disruption.
