Nature Studies Examine Native RNA Sequencing, Nanopore Sequencing Approach to Analyze STR Expansions

Nov 21, 2019

The native RNA sequencing and analysis of a human poly(A) transcriptome using the Oxford Nanopore Technologies platform is described in a new study in Nature Methods this week. An international research team reports generating 9.9 million aligned sequence reads for the human cell line GM12878 using 30 MinION flow cells at six institutions. These native RNA reads, the authors write, had a median length of 771 bases and a maximum aligned length of over 21,000 bases.

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