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University of California, Berkeley, researcher and CRISPR pioneer Jennifer Doudna reviews the scientific, technical, and ethical aspects of using the genome editing technology for therapeutic applications in this week's Nature. In her review, she presents examples highlighting both the potential and pitfalls of these efforts, and calls for "active efforts to ensure that this breakthrough technology is used responsibly to treat, cure, and prevent genetic disease."

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Bloomberg reports AstraZeneca may conduct another study of its candidate SARS-CoV-2 vaccine after dosing error.

Moderna is applying for an Emergency Use Authorization for its coronavirus vaccine, according to the New York Times.

The National Health Service is to conduct a trial of Grail's blood-based screening test for cancer.

In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.

Dec
02
Sponsored by
Qiagen

The Phosphoinositide 3-Kinase (PI3K) pathway is one of the most frequently altered pathways in human cancer and plays a significant role in disease progression and resistance to endocrine therapy.

Dec
03
Sponsored by
Mission Bio

Recent work by many investigators has discovered that over the course of aging, hematopoietic stem cells (HSCs) commonly undergo clonal expansion. 

Dec
10
Sponsored by
Tecan

CRISPR has developed into a core tool to facilitate genome editing, inspiring transformative ideas in engineering biology. 

Dec
10
Sponsored by
Illumina

Numerous companies now offer non-invasive prenatal screening (testing), many on different technology platforms.