Musculoskeletal
News on in vitro diagnostics for musculoskeletal disorders.
Osteoarthritis Risk Genes, Treatment Targets Unearthed in GWAS Meta-Analysis
Researchers identified 962 osteoarthritis risk variants and potentially targetable effector genes using genetic data for 489,975 cases and nearly 1.5 million unaffected controls.
Low heteroplasmy can cause mitochondrial electron transport chain defects in a suite of syndromes, suggesting the need for functional studies in accurate diagnoses.
The paper shows how spatial biology technologies are helping researchers in fields where certain sample types were previously a barrier to progress.
Blood-Based Protein Markers Help Predict Who Will Develop Knee Osteoarthritis
Researchers found six proteins that could predict knee osteoarthritis years ahead of time by profiling serum proteins in individuals who did or did not go on to develop the condition.
Skeletal Muscle Cell Atlas Reveals Age-Related Shifts in Gene Expression, Cell Types
Researchers profiled expression patterns in individual cells from skeletal muscle samples taken from younger and older humans and mice.