News on in vitro diagnostics for musculoskeletal disorders.
Single-Cell, Spatial Genomics Studies Unravel Development of Fetal Spinal Cord
The findings, based on single-cell and spatial gene expression analysis of fetal spinal cord samples, could aid the development of spinal cord disease models.
Bionano Genomics Launches CLIA-Certified Laboratory, First OGM-Based Test
Bionano Laboratories will offer services to clinical customers seeking to implement OGM for routine diagnostic use.
Osteoarthritis GWAS Leads to Key Genes, Treatment Targets
With a genome-wide association study and functional follow-up analyses, investigators saw 100 osteoarthritis-related loci including variants in potentially targetable genes and pathways.
Facial Phenotyping of Siblings Helps Identify Genetic Loci Affecting Face Shape
Many but not all of the loci identified had previously been tied to embryonic facial development or the abnormal development of facial features.
Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk
The findings underscore the value of carrying out large-scale human genetic analyses as part of drug target identification and validation efforts.