Musculoskeletal
News on in vitro diagnostics for musculoskeletal disorders.
Osteoarthritis GWAS Leads to Key Genes, Treatment Targets
With a genome-wide association study and functional follow-up analyses, investigators saw 100 osteoarthritis-related loci including variants in potentially targetable genes and pathways.
Facial Phenotyping of Siblings Helps Identify Genetic Loci Affecting Face Shape
Many but not all of the loci identified had previously been tied to embryonic facial development or the abnormal development of facial features.
Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk
The findings underscore the value of carrying out large-scale human genetic analyses as part of drug target identification and validation efforts.
Personalis, Sarepta Therapeutics Exploring Immune Response to Precision Genetic Therapeutics
The companies are applying Personalis' technology to explore immune response to genetic therapeutics in Sarepta's pipeline.
Jackson Lab, Shriners Hospitals to Study Genetics of Pediatric Orthopedic Disorders
The alliance comes a few months after Shriners Hospitals established a new genomics institute in Tampa, Florida in partnership with Genome Medical.