Musculoskeletal News on in vitro diagnostics for musculoskeletal disorders. Osteoarthritis GWAS Leads to Key Genes, Treatment Targets With a genome-wide association study and functional follow-up analyses, investigators saw 100 osteoarthritis-related loci including variants in potentially targetable genes and pathways. Facial Phenotyping of Siblings Helps Identify Genetic Loci Affecting Face Shape Many but not all of the loci identified had previously been tied to embryonic facial development or the abnormal development of facial features. Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk The findings underscore the value of carrying out large-scale human genetic analyses as part of drug target identification and validation efforts. Personalis, Sarepta Therapeutics Exploring Immune Response to Precision Genetic Therapeutics The companies are applying Personalis' technology to explore immune response to genetic therapeutics in Sarepta's pipeline. Jackson Lab, Shriners Hospitals to Study Genetics of Pediatric Orthopedic Disorders The alliance comes a few months after Shriners Hospitals established a new genomics institute in Tampa, Florida in partnership with Genome Medical. Dec 10, 2019 Invitae, BioMarin Partner on Access to Genetic Testing for Skeletal Dysplasias Oct 14, 2019 CureDuchenne, UC Irvine, RUCDR Partner on Muscular Dystrophy Biobank Oct 10, 2019 RNA-Seq Data Helps Focus Search for Rare Variants Oct 8, 2019 FDA Awards $2.4M to Vanderbilt Researcher for Duchenne Muscular Dystrophy Biomarker Study Jul 17, 2019 Multiple Sclerosis Single-Cell Transcriptome Study Highlights Affected Cell Types, Brain Regions May 1, 2019 Cleft Palate Study Shows Transcription Factor, Enhancer Roles in Related Developmental Processes Oct 19, 2018 Epilepsy, Developmental Disorders Linked to De Novo Mutations in Calcium Channel Subunit Oct 15, 2018 Sanofi Genzyme, PerkinElmer Launch Free Dx Program for Patients With Lysosomal Storage Disorders Aug 30, 2018 Bone Mineral Density at Forefront in Genetic Fracture Risk Meta-Analysis Jul 26, 2018 Bone Density GWAS Leads to New Loci, Osteoporosis Risk Score Jun 29, 2018 TRAF7 Mutations Implicated in Rare Multisystem Disorder Apr 27, 2018 Invitae, Biogen Partner on Free Spinal Muscular Atrophy Genetic Testing Program Breaking News In Brief This Week: Veracyte, Danaher, Chembio Diagnostics, and More Decode Genetics Plasma Proteome Study Improves Understanding of Disease Pathogenesis Euformatics Gains CE-IVD Mark for OmnomicsNGS People in the News: New Appointments at SomaLogic, 23andMe, Pacific Biosciences, More New Products Posted to GenomeWeb: GenDx, Eurofins Technologies, Codex DNA, More Variant Identified in Amish Population Appears to Protect From Cardiovascular Disease The Scan Steps for Quick Review The US Food and Drug Administration is preparing for the quick review of drugs and vaccines for the Omicron variant, according to the Wall Street Journal. Moving Away From Using Term 'Race' A new analysis finds that geneticists are using the term "race" in their papers less than in years past, as Science reports. Point of the Program The Guardian writes that some scientists have called the design of a UK newborn sequencing program into question. Science Papers Present Multi-Omic Analysis of Lung Cells, Regulation of Cardiomyocyte Proliferation In Science this week: a multi-omic analysis of lung cells focuses on RIT1-regulated pathways, and more.