NEW YORK (GenomeWeb) – Over the last few years, noninvasive prenatal testing has been established for fetal chromosomal aneuploidy screening as well as to look for subchromosomal aberrations, such as microdeletions and microduplications. However, when the mother unwittingly carries a chromosomal or subchromosomal abnormality herself, many types of NIPT that rely on counting DNA molecules cannot tell whether the fetus has inherited it as well.

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