Researchers Develop LR-PCR, NGS Combination Method to Detect PMS2 Gene Mutations

Aug 27, 2015

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NEW YORK(GenomeWeb) — Researchers from Baylor College of Medicine and Baylor Miraca Genetic Laboratories have created a more accurate method to detect mutations in the PMS2 gene, they reported today in the online version of the Journal of Molecular Diagnostics.

Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer (Lynch syndrome) and Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.

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