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MolecularMD Receives CAP Accreditation for Cambridge NGS Laboratory

NEW YORK (GenomeWeb) – MolecularMD has received accreditation from the College of American Pathologists for its next-generation sequencing laboratory in Cambridge, Mass.

The accreditation follows CLIA certification of the lab earlier this year. Molecular MD opened the lab in 2012 to complement its RT-PCR and immunohistochemistry laboratory in Portland, Ore.

The company has developed NGS cancer panels on multiple platforms, specializing in tissue- and blood-based assays for retrospective evaluations and prospective clinical trial enrollment.

The NGS laboratory has validated methods and platforms for circulating tumor DNA analysis. It recently validated the Thermo Fisher Ion AmpliSeq Cancer Hotspot Panel v2 for the detection of somatic hotspot mutations with less than 1 percent allele frequency in ctDNA.

The company has also adopted Thermo Fisher's Oncomine Cancer Research panel for the analysis of mutations, copy number alterations, and fusions in cancer genomes.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.