NEW YORK (GenomeWeb) – HTG Molecular Diagnostics announced yesterday that it has signed a master companion diagnostics development agreement with Merck KGaA, which will initially focus on a test for use with the German drugmaker's investigational Bruton's tyrosine kinase (BTK) inhibitor M7583.

BTK is an enzyme associated with B cell development and implicated in certain autoimmune diseases and cancers. Merck is developing M7583 as a treatment for B cell lymphoma and expects to begin clinical testing of the drug this year.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

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In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more

Jun
19
Sponsored by
Advanced Cell Diagnostics

This webinar will provide evidence for the use of RNA in situ hybridization (RNA ISH) as a replacement for immunohistochemistry (IHC) in cancer research and diagnostic applications.

Jun
21
Sponsored by
Roche

This webinar will provide a detailed look at how a genomics lab implemented next-generation sequencing (NGS) liquid biopsy assays into its in-house clinical research program.

Jun
26
Sponsored by
Lexogen

This webinar outlines a study that sought to characterize the landscape of alternative polyadenylation (APA) in the lung cancer transcriptome in order to gain insight into the role of APA in cancer progression.

Jul
10
Sponsored by
Qiagen

This webinar offers a look at how an advanced genetics laboratory implemented and validated a commercial bioinformatics system to help scale its operations.