Skip to main content
Premium Trial:

Request an Annual Quote

CorePath Laboratories, Cizzle Biotechnology Partner on Lung Cancer Blood Test 

NEW YORK – CorePath Laboratories announced on Thursday that it is partnering with UK-based Cizzle Biotechnology to develop and offer an early-stage lung cancer liquid biopsy test in the US. 

Cizzle, a spinout from the University of York, discovered that lung cancer cells produce the CIZ1B variant of the CIZ1 gene, whose protein is part of the nuclear structure and controls gene expression. Its test detects the C1Z1B variant in blood samples and is designed to address false positive rates in low-dose CT scanning to avoid unnecessary invasive testing. 

The companies signed a letter of intent for a strategic alliance in which CorePath, a full-service CLIA-certified and CAP-accredited cancer reference laboratory based in San Antonio, Texas, will commercialize the assay in the US with Cizzle receiving a proposed 15 percent royalties on all product and services offerings using CIZ1B in the US, according to a recorded interview with Cizzle Executive Chairman Allan Syms posted on the company’s website. 

"The agreement with Cizzle Biotechnology represents a significant opportunity to provide early and cost-effective lung cancer detection via a simple and quick blood test which will result in significant cost savings downstream, avoiding expensive treatment, hospital admissions and ultimately saving lives," Aamir Ehsan, CEO of CorePath, said in a statement. 

The Scan

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.

Sequencing Analysis Examines Gene Regulatory Networks of Honeybee Soldier, Forager Brains

Researchers in Nature Ecology & Evolution find gene regulatory network differences between soldiers and foragers, suggesting bees can take on either role.

Analysis of Ashkenazi Jewish Cohort Uncovers New Genetic Loci Linked to Alzheimer's Disease

The study in Alzheimer's & Dementia highlighted known genes, but also novel ones with biological ties to Alzheimer's disease.

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.