NEW YORK (GenomeWeb) – While it is known that environmental changes in an organism can trigger changes in its progeny for three or more generations, the exact mechanisms behind such transgenerational epigenetic effects remain unclear.

New research out of the University of Maryland, however, shows that RNAi-inducing double-stranded RNA molecules produced in the neurons of the model organisms Caenorhabditis elegans can be transmitted into the worm's germline, resulting in a gene-silencing effect that can persist for over 25 generations.

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US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

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Sep
12
Sponsored by
PerkinElmer

This webinar will cover recent advances in the use of CRISPR for generating animal models and cell lines.