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Bioneer Wins Grant to Develop RNAi Drug for Dengue Fever


NEW YORK (GenomeWeb) – South Korea's Bioneer announced that it has received a two-year, $1.3 million grant from the Korea Health Industry Development Institute to develop an siRNA-based therapy for dengue fever.

The therapeutic is based on Bioneer's so-called self-assembled micelle inhibitory RNA, or SAMiRNA, nanoparticle technology, and incorporates siRNAs targeting the dengue virus genome.

According to the company, it has received $500,000 of the award to conduct in vivo testing of its drug in a mouse model of dengue virus infection, which will be run in collaboration with the La Jolla Institute for Allergy and Immunology.

Upon successful completion of this first stage of the project, Bioneer is eligible to receive the remaining $800,000 in 2015.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.