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NEW YORK (GenomeWeb) – Researchers from Alnylam Pharmaceuticals this week published a study describing the company's development of GalNAc conjugates, which Alnylam is using with all of its newest drug candidates to deliver siRNAs into the liver.

The technology is based on N-acetylgalactosamine ligands, which have a high affinity for the asialoglycoprotein (ASGPR) receptors expressed on the surface of hepatocytes. While the concept of using these ligands for drug delivery in not new, doing so has been a challenge.

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The Hastings Center's Erik Parens argues in a Scientific American opinion piece that the current pandemic underscores the need to reconsider the hope placed in genomic medicine. 

The Los Angeles Times writes that Operation Warp Speed has an ambitious timeline for developing a COVID-19 vaccine.

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