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A new study in the New England Journal of Medicine shows that there are still places where we could use a little more knowledge, says Yale cardiologist Harlan Krumholz in Forbes. The study compares different ways of using diuretics to treat patients with heart failure, but what it really shows, Krumholz says, is the need for more comparative effectiveness research.

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The US Food and Drug Administration is to announce stricter standards for emergency authorizations of SARS-CoV-2 vaccines, reports the Washington Post.

The Associated Press reports Johnson & Johnson is starting a late-stage clinical trial of its candidate SARS-CoV-2 vaccine.

Bloomberg reports the budget of Operation Warp Speed is actually $18 billion, higher than the number typically cited.

In Genome Research this week: genomic analysis reveals role of super-spreaders in SARS-CoV-2, epigenetic drivers of cancer, and more.