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A new study in the New England Journal of Medicine shows that there are still places where we could use a little more knowledge, says Yale cardiologist Harlan Krumholz in Forbes. The study compares different ways of using diuretics to treat patients with heart failure, but what it really shows, Krumholz says, is the need for more comparative effectiveness research.

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New analyses indicate the P.1 variant found in Brazil may be able to infect people who have already had COVID-19, the New York Times reports.

According to CNBC, Novavax's CEO says its vaccine could be authorized in the US as early as May.

The US National Institutes of Health has a new initiative to address structural racism in biomedical research.

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.