NEW YORK (GenomeWeb) – Researchers from the University of Southampton have developed and published a method that uses Illumina HumanMethylation450 BeadChip arrays to conduct genome-wide methylation analysis in single samples without requiring large case-control cohorts.

The team shared its results in a study published last month in Clinical Epigenetics, showing that the method reliably picked up previously known and also novel methylated sites in patients with ultra-rare imprinting disorders.

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