Study Shows Prognostic Significance of Loss of Heterozygosity in AML, Supports Array-based Testing

Jun 23, 2015

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NEW YORK (GenomeWeb) – In a new study, researchers from the Fred Hutchinson Cancer Research Center have demonstrated that copy-neutral loss of heterozygosity has a clear and independent prognostic significance in patients with acute myeloid leukemia.

The data, published recently ahead of print in the journal Cancer, also support the clinical utility of array-based approaches, which can detect these genomic features in addition to better established markers like copy number alterations.

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