NEW YORK (GenomeWeb) – In a new study, researchers from the Fred Hutchinson Cancer Research Center have demonstrated that copy-neutral loss of heterozygosity has a clear and independent prognostic significance in patients with acute myeloid leukemia.

The data, published recently ahead of print in the journal Cancer, also support the clinical utility of array-based approaches, which can detect these genomic features in addition to better established markers like copy number alterations.