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People in the News: Patrick Roche, Trilochan Sahoo

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Patrick Roche has joined HTG Molecular Diagnostics as its new senior vice president for IVD assay development, HTG said last week.

Roche comes to HTG from Ventana Medical Systems, where he was VP of translational diagnostics and led companion diagnostics development efforts with pharmaceutical partners. Before Ventana, Roche was director of the immunohistochemistry clinical lab at the Mayo Clinic.


Molecular diagnostics firm CombiMatrix has hired Trilochan Sahoo as its new director of cytogenetics.

Sahoo will report to Chief Medical Officer Wes Tyson. Before joining CombiMatrix, Sahoo was senior director of clinical cytogenetics at Quest Diagnostics' Nichols Institute.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.