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People in the News: Oct 4, 2011

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David Ledbetter has joined CombiMatrix's medical advisory board.

Ledbetter is a director of the International Standards for Cytogenomic Arrays Consortium and currently serves as the executive vice president and chief scientific officer at Geisinger Health System. He has also held academic and genetics-related positions at Emory University School of Medicine, the University of Chicago, the National Institutes of Health, and Baylor College of Medicine.

Ledbetter holds a BS in psychology from Tulane University and a PhD in behavioral genetics and psychology from the University of Texas. He is a founding fellow of the American College of Medical Genetics and has served on the boards of directors of the American Society of Human Genetics and the ACMG.

BioArray News interviewed Ledbetter about his role at Geisinger earlier this year (BAN 1/11/11).


Expression Analysis has hired Tyler Aldredge as vice president of laboratory operations. Aldredge was most recently director of laboratory operations at Genzyme Genetics. Prior to that, he held positions at the Broad Institute, the Harvard University Center for Genomic Research, Sanofi, Codon Devices, and Genome Therapeutics.

The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.