Skip to main content
Premium Trial:

Request an Annual Quote

NIH Awards Akonni $300K to Develop System to ID Disease in CSF

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Akonni Biosystems today announced the National Institutes of Health has awarded it $300,000 to develop nucleic acid extraction and microarray-based testing systems for the identification of human disease in cerebrospinal fluid.

Specifically, the Frederick, Md.-based company is using the grant to develop a closed amplicon RT-PCR microarray for detecting enterovirus, herpes viruses, and West Nile virus in CSF. The herpes viruses targeted by the technology include herpes simplex virus types 1 and 2; varicella-zoster virus; cytomegalovirus; and human herpesvirus type 6.

The Laboratory of Viral Diseases at the Wadsworth Center in Albany, NY, is collaborating on the project. Together it and Akonni will "study, develop, and test a 'closed amplicon' gel element of RT-PCR and contribute to the development of more rapid, affordable, and comprehensive methods for diagnosing viral encephalitis and meningitis," Akonni said.

In a statement, Kevin Banks, vice president of sales and marketing for Akonni, said that "[c]ombining RT-PCR with our proprietary gel-drop microarray platform in a self-contained microfluidic chamber will further enhance our ability to develop and deploy multi-test panels to affordably and rapidly detect viruses, bacteria, fungi, and parasites in a single patient sample."

The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.