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New Product Watch: Apr 19, 2010


Affymetrix this week launched its MIP Copy Number Service through its research services laboratory.

The service is run on the company's MIP 330K Cancer Panel and enables researchers to obtain high-quality, allele-specific copy number data from formalin-fixed, paraffin-embedded samples.

According to the firm, the availability of allele and copy number data on a single platform provides a comprehensive tool to evaluate risk factors for the early stages of cancer and disease relapse.

Gentel Biosciences has launched APiX View Detection Kits for chromogenic detection of protein microarrays, including reverse-phase protein chips such as Protein Biotechnologies' SomaPlex arrays.

APiX chromogenic technology allows for the detection of any biotinylated molecule, generating light grey-to-black spots that are visible to the eye and can be scanned with the Gentel Proteomics Multi-System, the firm said.

Gentel said the new kits expand the application of its APiX technology to include not only antibody and protein arrays on clear glass slides, but also tumor lysate arrays on porous nitrocellulose surfaces. Protein Biotechnologies said in a statement that the new kits could be used together with its arrays.

Roche NimbleGen said last week that it will now offer 2-micron resolution scanning on its MS 200 Microarray Scanner for its comparative genomic hybridization and gene expression arrays. The service upgrade is available through Roche NimbleGen's services facility in Reykjavik, Iceland, or via one of its certified service providers, the firm said.

Ariadne has released Pathway Studio Explore to help users visualize pathways for data obtained using the Affymetrix GeneAtlas microarray system.

Pathway Studio Explore helps researchers build and study protein interaction networks and perform network analysis of experimental data, according to Ariadne. The software also offers a data analysis and visualization tool.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.