Exiqon this week launched the sixth generation of its Mircury LNA microRNA Arrays for expression profiling of microRNA from human, mouse, and rat.
The new arrays have 2,361 unique capture probes covering all mature human, mouse, rat, and related viral microRNA sequences as annotated in miRBase version 16.0. This is an increase of 500 microRNA capture probes compared with the fifth generation of the firm's microRNA array. The array also contains capture probes for 66 internally discovered miRPlus microRNAs.
CGC Genetics recently began offering testing for Noonan syndrome and other genetically related syndromes. The assay runs on the Illumina BeadXpress system.
This prenatal diagnostic test was developed to complement clinical diagnosis in cases where there is a suspicion of Noonan syndrome, such as increased nuchal translucency with normal chromosomes. In total, the assay includes 52 point mutations that are associated with Noonan syndrome as well as a differential diagnosis for Costello, LEOPARD, and cardiofaciocutaneous syndromes.