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New Product Watch: Dec 7, 2010

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Exiqon this week launched the sixth generation of its Mircury LNA microRNA Arrays for expression profiling of microRNA from human, mouse, and rat.

The new arrays have 2,361 unique capture probes covering all mature human, mouse, rat, and related viral microRNA sequences as annotated in miRBase version 16.0. This is an increase of 500 microRNA capture probes compared with the fifth generation of the firm's microRNA array. The array also contains capture probes for 66 internally discovered miRPlus microRNAs.


CGC Genetics recently began offering testing for Noonan syndrome and other genetically related syndromes. The assay runs on the Illumina BeadXpress system.

This prenatal diagnostic test was developed to complement clinical diagnosis in cases where there is a suspicion of Noonan syndrome, such as increased nuchal translucency with normal chromosomes. In total, the assay includes 52 point mutations that are associated with Noonan syndrome as well as a differential diagnosis for Costello, LEOPARD, and cardiofaciocutaneous syndromes.

The Scan

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.

Estonian Biobank Team Digs into Results Return Strategies, Experiences

Researchers in the European Journal of Human Genetics outline a procedure developed for individual return of results for the population biobank, along with participant experiences conveyed in survey data.

Rare Recessive Disease Insights Found in Individual Genomes

Researchers predict in Genome Medicine cross-population deletions and autosomal recessive disease impacts by analyzing recurrent nonallelic homologous recombination-related deletions.

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.