NEW YORK (GenomeWeb) – Immune-related expression profiles in kidney transplant recipients may help predict which of those individuals accept the new organ without having to endure a lifetime of immune-suppressing drugs.

Researchers from Northwestern University, the University of Virginia, and elsewhere used a combination of microarrays and/or RT-qPCR to assess gene expression and microRNA profiles in kidney graft samples from seven kidney transplant "tolerant" individuals, who received engineered donor stem cells and did not require chronic immunosuppression post-surgery.

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